Archive for May, 2017

Source: https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnci/djx086 The US Food and Drug Administration recently announced the need to evaluate the association between PDE5is and melanoma. We performed a meta-analysis on the association between PDE5i and melanoma using random effects models and examined whether it met Hill’s criteria for causality. A systematic search of Medline, EMBASE, and the Cochrane Library from […]

The forehead is often the first place many men and women start to notice those first signs of aging. Lines, wrinkles and creases may appear due to loss of volume, loss of elasticity, and gravity that can cause us to look older and more run down than we are. Some people are born with a […]

In this study, Fang et al explored the relationship between melanoma outcomes, obesity, and chronic inflammation. Obesity has been associated with development of cancers including melanoma. Adipose tissue produces signaling molecules, such as leptin, which are thought to play a role in cancer progression. Signaling from fat tissue may result in chronic inflammation, as happens […]

Recent study showing that although sun bed use caused a transient increase in vitamine d levels after continued sun bed use vitamin D levels went back down and there was benefit to overall well being. Although serum vitamin D levels are transiently increased after sunbed use, longer-term increases in serum vitamin D levels are not […]

Article Outline Patients and Methods Study Setting Study Criteria Data Collection Statistical Analyses Results Basal Cell Carcinoma Cutaneous Squamous Cell Carcinoma Discussion Basal Cell Carcinoma Cutaneous Squamous Cell Carcinoma Younger Populations Study Limitations Conclusion Patients and Methods Study Setting In 2010, Olmsted County had a population of 144,248.20 Although the average socioeconomic status, proportion of […]

A new article published online in February explores the outcomes of Melanoma In Situ (MIS) when teated with Mohs Micrographic Surgery vs. Wide Local Excision. The take home message from this study is that the Mohs Micrographic Surgery (MMS) is at least as effective as wide local excision (WLE), (with the potential added benefit of […]

The prognosis for a melanoma is very closely correlated to how deeply it has invaded into the skin (“Breslow Depth”). The for deeper melanomas the risk of spead to lymph nodes is large enough to merit “sentinal node biopsy”. a surgery where radioactive die is injected to tract the first lymphnodes that drain the area […]