When most of us think of the BRCA 1 and BRCA 2 mutations we think of women and breast cancer. However BRCA mutations can increase the risk of other malignancies including melanoma. A recent study from Israel has show that men with these mutations are also at risk. They found that men with BRCA 1 or BRCA 2 mutations were at increased risk of melanoma and pancreatic cancer as well as breast cancer, (yes men can get breast cancer too!), and unique to men is an increased risk of prostate cancer. They recommend that men with these mutations get screened for prostate cancer and that both men and women with these mutations get screened for breast and pancreatic cancer as well as melanoma.

Citation:

JAMA Oncol. Published online April 12, 2018.