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Category Archives: Plastic Surgery

More Is Not Always Better

In the past, lymph node dissection was thought to benefit patients with melanoma. A recent study in the New England Journal of Medicine, however, has shown that it does not seem to have any added benefits. The study concluded that complete lymph node removal was no better than less extensive surgery and observation for extending […]

Oral vitamin D rapidly attenuates inflammation from sunburn: an interventional study.

The diverse immunomodulatory effects of vitamin D are increasingly being recognized. However, the ability of oral vitamin D to modulate acute inflammation in vivo has not been established in humans. In a double-blinded, placebo-controlled interventional trial, twenty healthy adults were randomized to receive either placebo or a high dose of vitamin D3 (cholecalciferol) one hour […]

Meta-Analysis of the Association Between Phosphodiesterase Inhibitors (PDE5Is) and Risk of Melanoma

Source: https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnci/djx086 The US Food and Drug Administration recently announced the need to evaluate the association between PDE5is and melanoma. We performed a meta-analysis on the association between PDE5i and melanoma using random effects models and examined whether it met Hill’s criteria for causality. A systematic search of Medline, EMBASE, and the Cochrane Library from […]

Brow Lift Santa Monica

The forehead is often the first place many men and women start to notice those first signs of aging. Lines, wrinkles and creases may appear due to loss of volume, loss of elasticity, and gravity that can cause us to look older and more run down than we are. Some people are born with a […]

Yet Another Reason to Watch Your Weight

In this study, Fang et al explored the relationship between melanoma outcomes, obesity, and chronic inflammation. Obesity has been associated with development of cancers including melanoma. Adipose tissue produces signaling molecules, such as leptin, which are thought to play a role in cancer progression. Signaling from fat tissue may result in chronic inflammation, as happens […]

Sunbeds

Recent study showing that although sun bed use caused a transient increase in vitamine d levels after continued sun bed use vitamin D levels went back down and there was benefit to overall well being. Although serum vitamin D levels are transiently increased after sunbed use, longer-term increases in serum vitamin D levels are not […]

Incidence and Trends of Basal Cell Carcinoma and Cutaneous Squamous Cell Carcinoma

Article Outline Patients and Methods Study Setting Study Criteria Data Collection Statistical Analyses Results Basal Cell Carcinoma Cutaneous Squamous Cell Carcinoma Discussion Basal Cell Carcinoma Cutaneous Squamous Cell Carcinoma Younger Populations Study Limitations Conclusion Patients and Methods Study Setting In 2010, Olmsted County had a population of 144,248.20 Although the average socioeconomic status, proportion of […]

Comparing Melanoma In Situ Treated With Mohs Micrographic Surgery vs. Wide Local Excision

A new article published online in February explores the outcomes of Melanoma In Situ (MIS) when teated with Mohs Micrographic Surgery vs. Wide Local Excision. The take home message from this study is that the Mohs Micrographic Surgery (MMS) is at least as effective as wide local excision (WLE), (with the potential added benefit of […]

Prognostic Role of Histologic Regression in Primary Cutaneous Melanoma

The prognosis for a melanoma is very closely correlated to how deeply it has invaded into the skin (“Breslow Depth”). The for deeper melanomas the risk of spead to lymph nodes is large enough to merit “sentinal node biopsy”. a surgery where radioactive die is injected to tract the first lymphnodes that drain the area […]

Anti-Aging Gene Identified in Melanoma Treatment

At The Wistar Institute in Philadelphia researchers have discovered that an anti-diabetic drug stimulates an anti-aging gene which has the ability to restrain the progress of melanoma in older people. Melanoma is a common form of skin cancer that is seen more frequently in patients who are older. While target therapies being used currently to […]

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